Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13670442 | 0.85 | MAPT (0.65) | MAPTKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4704685 | 0.82 | MAPT (0.61) | MAPTKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL22690991 | 0.82 | MAPT (0.61) | MAPTKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4704433 | 0.80 | KDM4E (0.55) | MAPTKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL13154843 | 0.78 | KDM4E (0.65) | MAPTKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4703109 | 0.74 | KDM4E (0.56) | MAPTKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4704337 | 0.71 | KDM4E (0.53) | MAPTKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL13154827 | 0.70 | MAPT (0.46) | MAPTKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5996852 | 0.68 | MAPT (0.44) | MAPTKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL21358080 | 0.67 | KDM4E (0.34) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060247320-A1 | Compounds for inhibiting KSP kinesin activity | SCHERING CORPORATION | 2006-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247320-A1 | Compounds for inhibiting KSP kinesin activity | KIFC1, KIF5B, KIF2C | MAPT 434/4885KDM4E 501/4885ALDH1A1 2371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.