Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL954785 | 0.73 | MEN1 (0.43) | MEN1RAB9AKMT2AHTR1ADRD2 | |
| SCHEMBL5115890 | 0.70 | MEN1 (0.59) | MEN1RAB9AKMT2AHTR1ADRD2 | |
| SCHEMBL5115896 | 0.70 | MEN1 (0.58) | MEN1RAB9AKMT2AHTR1ADRD2 | |
| SCHEMBL13670533 | 0.66 | MAPT (0.32) | — | |
| SCHEMBL13670754 | 0.65 | POLB (0.33) | — | |
| SCHEMBL2609332 | 0.65 | KMT2A (0.60) | MEN1RAB9AKMT2ATRPV3HTR1A | |
| SCHEMBL5109003 | 0.65 | TDP1 (0.42) | MEN1RAB9AKMT2ACYP1A2CYP3A4 | |
| SCHEMBL5115440 | 0.65 | RAB9A (0.46) | MEN1RAB9AKMT2AHTR1ADRD2 | |
| SCHEMBL954180 | 0.65 | ALDH1A1 (0.36) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL25885404 | 0.65 | MEN1 (0.54) | MEN1RAB9AKMT2ATRPV3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009118087-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2009-10-01 | — | — | WO | disclosed |