Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL954180 | 0.76 | ALDH1A1 (0.36) | POLBMAPTALDH1A1TDP1 | |
| SCHEMBL13670533 | 0.75 | MAPT (0.32) | POLBMAPTALDH1A1TDP1 | |
| SCHEMBL17032805 | 0.71 | ALDH1A1 (0.46) | POLBMAPTALDH1A1TSHRTDP1 | |
| SCHEMBL13231060 | 0.68 | ACHE (0.33) | MAPTALDH1A1GLATSHRTDP1 | |
| SCHEMBL13231261 | 0.67 | SYK (0.34) | MAPTALDH1A1GLATSHRTDP1 | |
| SCHEMBL30811084 | 0.67 | CCR1 (0.43) | MAPTALDH1A1TSHRTDP1 | |
| SCHEMBL5109003 | 0.66 | TDP1 (0.42) | POLBMAPTALDH1A1TSHRTDP1 | |
| SCHEMBL954531 | 0.66 | SMN1; SMN2 (0.33) | POLBALDH1A1TDP1 | |
| SCHEMBL13670532 | 0.65 | MEN1 (0.34) | — | |
| SCHEMBL13231057 | 0.65 | ENPP1 (0.38) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009118087-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2009-10-01 | — | — | WO | disclosed |