Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.41 |
| ▸ | LOX | P28300 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 3/20 | 0.36 |
| ▸ | F10 | P00742 | 3/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13670082 | 0.82 | MAP4K4 (0.40) | L3MBTL1MAP4K4HTTALDH1A1MEN1 | |
| SCHEMBL15871857 | 0.76 | LOXL2 (0.55) | LOXL2LOXF2F10PRSS1 | |
| SCHEMBL954527 | 0.76 | LOXL2 (0.48) | LOXL2LOXSMN1; SMN2F2F10 | |
| SCHEMBL25946356 | 0.76 | F2 (0.42) | LOXL2LOXL3MBTL1SMN1; SMN2F2 | |
| SCHEMBL2521152 | 0.73 | LTA4H (0.58) | L3MBTL1SMN1; SMN2F2F10PRSS1 | |
| SCHEMBL8972092 | 0.73 | TSHR (0.47) | LOXL2LOXL3MBTL1SMN1; SMN2F2 | |
| SCHEMBL13670533 | 0.72 | MAPT (0.32) | ALDH1A1MAPT | |
| SCHEMBL13670464 | 0.72 | BRD4 (0.42) | ALDH1A1HPGD | |
| SCHEMBL9198043 | 0.69 | KCNH2 (0.44) | L3MBTL1SMN1; SMN2F2F10PRSS1 | |
| SCHEMBL9105297 | 0.69 | LOXL2 (0.45) | LOXL2LOXL3MBTL1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009118087-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2009-10-01 | — | — | WO | disclosed |