Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14853466 | 0.87 | LMNA (0.50) | NPC1RAB9AALDH1A1SMN1; SMN2RECQL | |
| SCHEMBL14853420 | 0.85 | CYP2C19 (0.55) | NPC1RAB9AALDH1A1SMN1; SMN2RECQL | |
| SCHEMBL14853257 | 0.83 | ALDH1A1 (0.54) | NPC1RAB9AALDH1A1SMN1; SMN2RECQL | |
| SCHEMBL14853494 | 0.82 | SMN1; SMN2 (0.56) | NPC1RAB9AALDH1A1SMN1; SMN2RECQL | |
| SCHEMBL13643 | 0.80 | ALDH1A1 (0.54) | NPC1RAB9AALDH1A1SMN1; SMN2RECQL | |
| SCHEMBL17354497 | 0.78 | CACNA1H (0.54) | NPC1RAB9AALDH1A1SMN1; SMN2RECQL | |
| SCHEMBL17354494 | 0.76 | SMN1; SMN2 (0.59) | NPC1RAB9AALDH1A1SMN1; SMN2RECQL | |
| SCHEMBL17354487 | 0.76 | MTNR1A (0.61) | NPC1RAB9AALDH1A1SMN1; SMN2RECQL | |
| SCHEMBL14055 | 0.75 | CYP2C19 (0.55) | NPC1RAB9AALDH1A1LMNAMAPT | |
| SCHEMBL14850294 | 0.73 | LMNA (0.47) | NPC1RAB9AALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011047323-A2 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X PHARMACEUTICALS, INC. (US) | 2011-04-21 | — | — | WO | disclosed |