SCHEMBL1367166

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1367167	1.00	JAK2 (0.59)	JAK2JAK3JAK1TYK2PRCP
	SCHEMBL1367538	0.91	JAK2 (0.64)	JAK2JAK3JAK1TYK2PRCP
	SCHEMBL1367542	0.91	JAK2 (0.64)	JAK2JAK3JAK1TYK2PRCP
	SCHEMBL30574675	0.91	JAK2 (0.61)	JAK2JAK3JAK1TYK2PRCP
	SCHEMBL1368552	0.90	JAK2 (0.64)	JAK2JAK3JAK1TYK2PRCP
	SCHEMBL1368556	0.90	JAK2 (0.64)	JAK2JAK3JAK1TYK2PRCP
	SCHEMBL12141023	0.89	JAK2 (0.59)	JAK2JAK3JAK1TYK2PRCP
	SCHEMBL30007786	0.89	JAK2 (0.59)	JAK2JAK3JAK1TYK2PRCP
	Hydrochloric Acid SCHEMBL1365579	0.89	JAK2 (0.62)	JAK2JAK3JAK1TYK2PRCP
	Hydrochloric Acid SCHEMBL1365582	0.89	JAK2 (0.62)	JAK2JAK3JAK1TYK2PRCP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.