Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25286492 | 1.00 | MMP2 (0.40) | MMP2ANPEPCHRNB2CHRNA4CHRNB4 | |
| SCHEMBL13672052 | 1.00 | MMP2 (0.40) | MMP2ANPEPCHRNB2CHRNA4CHRNB4 | |
| SCHEMBL22629334 | 1.00 | MMP2 (0.40) | MMP2ANPEPCHRNB2CHRNA4CHRNB4 | |
| SCHEMBL14403910 | 1.00 | MMP2 (0.40) | MMP2ANPEPCHRNB2CHRNA4CHRNB4 | |
| SCHEMBL14403914 | 0.88 | MMP2 (0.40) | MMP2ANPEPCHRNB2CHRNA4CHRNB4 | |
| SCHEMBL31664512 | 0.87 | MMP2 (0.42) | MMP2ANPEPCHRNB2CHRNA4CHRNB4 | |
| SCHEMBL27740704 | 0.87 | MMP2 (0.42) | MMP2ANPEPCHRNB2CHRNA4CHRNB4 | |
| SCHEMBL15796255 | 0.87 | MMP2 (0.42) | MMP2ANPEPCHRNB2CHRNA4CHRNB4 | |
| SCHEMBL13631040 | 0.82 | MMP2 (0.31) | MMP2ANPEP | |
| SCHEMBL13696040 | 0.80 | CHRNB2 (0.47) | MMP2ANPEPCHRNB2CHRNA4CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122772-A1 | OXIME DERIVATIVES USEFUL AS T CELL ACTIVATORS | GOSSAMER BIO SERVICES, INC. (US) | 2023-06-29 | — | — | WO | disclosed |
| US-7601714-B2 | Pyrimidine derivatives useful as inhibitors of PKC-theta | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2009-10-13 | — | — | US | disclosed |
| US-7601714-B2 | Pyrimidine derivatives useful as inhibitors of PKC-theta | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2009-10-13 | — | — | US | disclosed |