Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | ANPEP | P15144 | 2/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13696040 | 0.90 | CHRNB2 (0.47) | MMP2ANPEPCHRNB2CHRNA4CHRNB4 | |
| SCHEMBL13672046 | 0.87 | MMP2 (0.40) | MMP2ANPEPCHRNB2CHRNA4CHRNB4 | |
| SCHEMBL14403910 | 0.87 | MMP2 (0.40) | MMP2ANPEPCHRNB2CHRNA4CHRNB4 | |
| SCHEMBL13672052 | 0.87 | MMP2 (0.40) | MMP2ANPEPCHRNB2CHRNA4CHRNB4 | |
| SCHEMBL14403914 | 0.87 | MMP2 (0.40) | MMP2ANPEPCHRNB2CHRNA4CHRNB4 | |
| SCHEMBL25286492 | 0.87 | MMP2 (0.40) | MMP2ANPEPCHRNB2CHRNA4CHRNB4 | |
| SCHEMBL22629334 | 0.87 | MMP2 (0.40) | MMP2ANPEPCHRNB2CHRNA4CHRNB4 | |
| SCHEMBL13436061 | 0.82 | MMP2 (0.41) | MMP2ANPEPCHRNB2CHRNA4CHRNB4 | |
| SCHEMBL15796255 | 0.80 | MMP2 (0.42) | MMP2ANPEPCHRNB2CHRNA4CHRNB4 | |
| SCHEMBL31664512 | 0.80 | MMP2 (0.42) | MMP2ANPEPCHRNB2CHRNA4CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101300252-B | Novel cycloalkane carboxamides as factor Xa inhibitors | HOFFMANN LA ROCHE | 2011-09-28 | — | — | CN | disclosed |
| CN-101300252-A | Novel cycloalkane carboxamides as factor Xa inhibitors | HOFFMANN LA ROCHE (CH) | 2008-11-05 | — | — | CN | disclosed |