Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 7/20 | 0.38 |
| ▸ | AVPR2 | P30518 | 6/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13672184 | 0.84 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AHTTTDP1 | |
| SCHEMBL13672414 | 0.84 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AHTTTDP1 | |
| SCHEMBL13672178 | 0.82 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AHTTTDP1 | |
| SCHEMBL13672519 | 0.81 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AHTTTDP1 | |
| SCHEMBL13672521 | 0.81 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AHTTTDP1 | |
| SCHEMBL13672416 | 0.81 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2AHTTTDP1 | |
| SCHEMBL13672523 | 0.81 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AHTTTDP1 | |
| SCHEMBL13672415 | 0.80 | CYP3A4 (0.44) | ALDH1A1MEN1KMT2AHTTTDP1 | |
| SCHEMBL13672177 | 0.80 | DPP4 (0.41) | ALDH1A1MEN1KMT2AHTTTDP1 | |
| SCHEMBL13672173 | 0.80 | PREP (0.45) | ALDH1A1MEN1KMT2AHTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090264414-A1 | Amide Derivatives and Pharmaceutical Use Thereof | HIGH POINT PHARMACEUTICALS, LLC (US) | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264414-A1 | Amide Derivatives and Pharmaceutical Use Thereof | HSD11B1, HSD11B2, HSD3B1 | ALDH1A1 232/4885MEN1 2564/4885KMT2A 2931/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.