SCHEMBL1367286

SCHEMBL1367286

CCO[Si](CCCN[C@@H](CC(=O)O)C(=O)O)(OCC)OCC

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 2/20 0.34
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.32
GNPAT O15228 1/20 0.31
CA2 P00918 1/20 0.31
CA4 P22748 1/20 0.31
CASP3 P42574 1/20 0.31
SUCNR1 Q9BXA5 2/20 0.30
NOD1 Q9Y239 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1367282 1.00 EPHX2 (0.34) EPHX2TSHRMAPK1GNPATCA2
SCHEMBL17505034 0.88 SMN1; SMN2 (0.35)
SCHEMBL4632552 0.88 ECE1 (0.35) TSHRMAPK1NOD1
SCHEMBL11905915 0.87 EPHX2 (0.33) EPHX2TSHRMAPK1GNPATCA2
SCHEMBL11905204 0.87 EPHX2 (0.33) EPHX2TSHRMAPK1GNPATCA2
SCHEMBL11905920 0.87 EPHX2 (0.33) EPHX2TSHRMAPK1GNPATCA2
SCHEMBL1369382 0.84 MAPK1 (0.38) EPHX2TSHRMAPK1GNPATCA2
SCHEMBL1369390 0.84 MAPK1 (0.38) EPHX2TSHRMAPK1GNPATCA2
Butane SCHEMBL16113854 0.84 EPHX2 (0.36) EPHX2TSHRMAPK1GNPATCA2
SCHEMBL16713052 0.83 MAPT (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9567354-B2 Amino acid-modified silane compounds and making method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-02-14 US claimed
US-20120209020-A1 AMINO ACID-MODIFIED SILANE COMPOUNDS AND MAKING METHOD SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-08-16 US claimed
CN-113195666-B Moisture-curable heat-sealing adhesive 思美定株式会社 2023-05-12 CN disclosed
CN-113195666-A Moisture-curable hot-melt adhesive 思美定株式会社 2021-07-30 CN disclosed
US-9567354-B2 Amino acid-modified silane compounds and making method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-02-14 US disclosed
US-20150274918-A1 MULTICOMPONENT SYSTEM FOR PRODUCTION OF ALKOXYSILANE-BASED SPRAY FOAMS MÖLNLYCKE HEALTH CARE AB (SE) 2015-10-01 US disclosed
US-20120209020-A1 AMINO ACID-MODIFIED SILANE COMPOUNDS AND MAKING METHOD SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-08-16 US disclosed
US-8067522-B2 Low viscosity, alkoxysilane-functional prepolymers and a process for their preparation BAYER MATERIALSCIENCE AG (DE) 2011-11-29 US disclosed
US-20070055035-A1 Low viscosity, alkoxysilane-functional prepolymers and a process for their preparation BAYER MATERIALSCIENCE AG 2007-03-08 US disclosed
EP-1685175-A1 POLYURETHANE COMPOSITIONS WITH NCO AND SILYL REACTIVITY Henkel Kommanditgesellschaft auf Aktien (DE) 2006-08-02 EP disclosed
WO-2005049684-A1 POLYURETHANE COMPOSITIONS WITH NCO AND SILYL REACTIVITY HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2005-06-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120209020-A1 AMINO ACID-MODIFIED SILANE COMPOUNDS AND MAKING METHOD BCAT2, BCAT1, ASNS EPHX2 3907/4885TSHR 4355/4885MAPK1 1575/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.