SCHEMBL1369382

SCHEMBL1369382

CO[Si](CCCNC(CC(=O)O)C(=O)O)(OC)OC

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.38
TSHR P16473 1/20 0.37
EPHX2 P34913 2/20 0.33
GNPAT O15228 1/20 0.33
CA2 P00918 1/20 0.33
CA4 P22748 1/20 0.33
SUCNR1 Q9BXA5 5/20 0.32
MEN1 O00255 1/20 0.31
GAA P10253 1/20 0.31
KMT2A Q03164 1/20 0.31
TGFBR1 P36897 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1369390 1.00 MAPK1 (0.38) MAPK1TSHREPHX2GNPATCA2
Butane SCHEMBL16113854 0.95 EPHX2 (0.36) MAPK1TSHREPHX2GNPATCA2
SCHEMBL15011355 0.88 ECE1 (0.36) MAPK1TSHRCA2
SCHEMBL11905609 0.86 TSHR (0.36) MAPK1TSHREPHX2GNPATCA2
SCHEMBL11905332 0.86 TSHR (0.36) MAPK1TSHREPHX2GNPATCA2
SCHEMBL1368878 0.86 TSHR (0.36) MAPK1TSHREPHX2GNPATCA2
SCHEMBL27545312 0.85 MAPK1 (0.33) MAPK1TSHRMEN1GAAKMT2A
SCHEMBL23795575 0.85 SMN1; SMN2 (0.35) KMT2A
SCHEMBL1367286 0.84 EPHX2 (0.34) MAPK1TSHREPHX2GNPATCA2
SCHEMBL1367282 0.84 EPHX2 (0.34) MAPK1TSHREPHX2GNPATCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2970709-B1 SINGLE-COMPONENT MOISTURE-CURABLE COATINGS BASED ON N-SUBSTITUTED UREA POLYMERS WITH EXTENDED CHAINS AND TERMINAL ALKOXYSILANES US GOV SEC NAVY (US) 2017-10-18 EP claimed
US-9701868-B2 Single-component moisture-curable coatings based on N-substituted urea polymers with extended chains and terminal alkoxysilanes THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2017-07-11 US claimed
EP-1877459-B2 MOISTURE-CURABLE COMPOSITION FEATURING INCREASED ELASTICITY SIKA TECH AG (CH) 2017-06-14 EP claimed
US-9567354-B2 Amino acid-modified silane compounds and making method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-02-14 US claimed
EP-2970709-A1 SINGLE-COMPONENT MOISTURE-CURABLE COATINGS BASED ON N-SUBSTITUTED UREA POLYMERS WITH EXTENDED CHAINS AND TERMINAL ALKOXYSILANES The Government of the United States of America, as represented by the Secretary of the Navy (US) 2016-01-20 EP claimed
US-20150291837-A1 SINGLE-COMPONENT MOISTURE-CURABLE COATINGS BASED ON N-SUBSTITUTED UREA POLYMERS WITH EXTENDED CHAINS AND TERMINAL ALKOXYSILANES THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE NAVY 2015-10-15 US claimed
US-9139753-B2 Single-component moisture-curable coatings based on N-substituted urea polymers with extended chains and terminal alkoxysilanes THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2015-09-22 US claimed
WO-2014158535-A1 SINGLE-COMPONENT MOISTURE-CURABLE COATINGS BASED ON N-SUBSTITUTED UREA POLYMERS WITH EXTENDED CHAINS AND TERMINAL ALKOXYSILANES THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2014-10-02 WO claimed
US-20140275405-A1 SINGLE-COMPONENT MOISTURE-CURABLE COATINGS BASED ON N-SUBSTITUTED UREA POLYMERS WITH EXTENDED CHAINS AND TERMINAL ALKOXYSILANES THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE NAVY 2014-09-18 US claimed
US-20120209020-A1 AMINO ACID-MODIFIED SILANE COMPOUNDS AND MAKING METHOD SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-08-16 US claimed
EP-1877459-B1 MOISTURE-CURABLE COMPOSITION FEATURING INCREASED ELASTICITY SIKA TECHNOLOGY AG (CH) 2009-10-21 EP claimed
EP-4588949-A1 CURABLE SILANE-TERMINATED POLYMER COMPOSITION WITH IMPROVED ADHESION ON PLASTIC SUBSTRATES Sika Technology AG (CH) 2025-07-23 EP disclosed
US-11965056-B2 Drying agent for moisture-curing compositions COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2024-04-23 US disclosed
US-11499001-B2 Single-component polysiloxane non-skid / non-slip coatings THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2022-11-15 US disclosed
EP-3983495-A1 SINGLE-COMPONENT POLYSILOXANE NON-SKID / NON-SLIP COATINGS The Government of the United States of America, as represented by the Secretary of the Navy (US) 2022-04-20 EP disclosed
US-8067522-B2 Low viscosity, alkoxysilane-functional prepolymers and a process for their preparation BAYER MATERIALSCIENCE AG (DE) 2011-11-29 US disclosed
US-20070055035-A1 Low viscosity, alkoxysilane-functional prepolymers and a process for their preparation BAYER MATERIALSCIENCE AG 2007-03-08 US disclosed
US-6762270-B2 REACTION PRODUCT OF DIISOCAYANTE AND A POLYOXYALKYLENE DIOL WHEREIN THE REACTION IS STOPPED AFTER 50 TO 90% OF THE OH GROUPS OF POLYETHER REACTED, AND 50-10% OH GROUPS UNREACTED AND A COMPOUND HAVING ALKOXYSILANE AND AMINO GROUPS BAYER AKTIENGESELLSCHAFT (DE) 2004-07-13 US disclosed
US-6703453-B1 COMPOSITION WHICH COMPRISES ALKOXYSILANE-FUNCTIONAL POLYURETHANE, FILLER, REACTION PRODUCT OF AMINOSILANE AND DIALKYL MALEATE OR FUMARATE, AND ORGANOMETALLIC COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 2004-03-09 US disclosed
US-20030153712-A1 Polyurethane prepolymers with reduced functionality having terminal alkoxysilane and OH groups, a method of preparing them and their use BAYER AKTIENGESELLSCHAFT (DE) 2003-08-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120209020-A1 AMINO ACID-MODIFIED SILANE COMPOUNDS AND MAKING METHOD BCAT2, BCAT1, ASNS MAPK1 1575/4885TSHR 4355/4885EPHX2 3907/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.