Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | STK10 | O94804 | 3/20 | 0.39 |
| ▸ | GSK3B | P49841 | 3/20 | 0.39 |
| ▸ | SLK | Q9H2G2 | 3/20 | 0.39 |
| ▸ | GSK3A | P49840 | 2/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | STK33 | Q9BYT3 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | TLK1 | Q9UKI8 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13673438 | 0.71 | STK10 (0.38) | LMNAADORA2BSTK10GSK3BSLK | |
| SCHEMBL12136946 | 0.68 | ACACB (0.44) | LMNAGSK3BGSK3AACACBACACA | |
| SCHEMBL1900642 | 0.67 | GSK3B (0.39) | STK10GSK3BSLKGSK3ACLK2 | |
| SCHEMBL11941312 | 0.66 | ACACB (0.44) | ACACBACACAPPOX | |
| SCHEMBL4433853 | 0.65 | ADAM17 (0.39) | LMNATRPV4 | |
| SCHEMBL13672536 | 0.64 | PRKCA (0.42) | STK10GSK3BSLKALDH1A1MEN1 | |
| SCHEMBL14609665 | 0.64 | GSK3B (0.43) | GSK3BACACBACACAPPOXALDH1A1 | |
| SCHEMBL5963474 | 0.63 | RECQL (0.41) | GSK3BGSK3AACACBACACA | |
| SCHEMBL12658142 | 0.63 | ACACB (0.39) | STK10GSK3BSLKGSK3ACLK2 | |
| SCHEMBL4856796 | 0.63 | CHEK1 (0.60) | GSK3BGSK3ACLK2CLK4TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741700-B1 | 1-H-3-ARYLPYRROLIDINE-2,4-DIONE DERIVATIVES AS PEST-CONTROL AGENTS | BAYER CROPSCIENCE AG (DE) | 2009-10-07 | — | — | EP | disclosed |