Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 5/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 3/20 | 0.34 |
| ▸ | PLK4 | O00444 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | MARK3 | P27448 | 1/20 | 0.34 |
| ▸ | FLT4 | P35916 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13960144 | 0.86 | GSK3B (0.40) | GSK3BCDK4CCND1GSK3APLK4 | |
| SCHEMBL12658142 | 0.84 | ACACB (0.39) | GSK3BCDK4CCND1ERN1GSK3A | |
| SCHEMBL1901580 | 0.83 | GSK3B (0.35) | GSK3BCDK4CCND1ERN1GSK3A | |
| SCHEMBL12658140 | 0.82 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL12658245 | 0.80 | GSK3B (0.34) | GSK3BCDK4CCND1GSK3APLK4 | |
| SCHEMBL12658337 | 0.80 | CNR2 (0.36) | GSK3BCDK4CCND1GSK3APLK4 | |
| SCHEMBL12724985 | 0.79 | ACACB (0.46) | GSK3BCDK4CCND1ACACBACACA | |
| SCHEMBL1898467 | 0.79 | ACACB (0.51) | GSK3BCDK4CCND1ACACBACACA | |
| SCHEMBL10230210 | 0.78 | SLK (0.36) | GSK3BCDK4CCND1ERN1GSK3A | |
| SCHEMBL12658359 | 0.77 | ERN1 (0.35) | GSK3BCDK4CCND1ERN1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2320735-A2 | HERBICIDAL COMBINATION WITH DIMETHOXY-TRIAZINYL-SUBSTITUTED DIFLUOROMETHANE SULFONYLANILIDES | Bayer CropScience AG (DE) | 2011-05-18 | — | — | EP | claimed |
| US-20100304971-A1 | HERBICIDAL COMBINATION | BAYER CROPSCIENCE AG (DE) | 2010-12-02 | — | — | US | claimed |
| EP-2205092-A2 | HERBICIDAL COMBINATION | Bayer CropScience AG (DE) | 2010-07-14 | — | — | EP | claimed |
| US-20100093542-A1 | HERBICIDE COMBINATION COMPRISING DIMETHOXYTRIAZINYL SUBSTITUTED DIFLUOROMETHANESULFONYLANILIDES | BAYER CORPSCIENCE AG (DE) | 2010-04-15 | — | — | US | claimed |
| WO-2010017923-A2 | HERBICIDAL COMBINATION WITH DIMETHOXY-TRIAZINYL-SUBSTITUTED DIFLUOROMETHANE SULFONYLANILIDES | BAYER CROPSCIENCE AG (DE) | 2010-02-18 | — | — | WO | claimed |
| WO-2009053053-A2 | HERBICIDAL COMBINATION | BAYER CROPSCIENCE AG (DE) | 2009-04-30 | — | — | WO | claimed |
| CN-102186348-A | Herbicidal combination comprising dimethoxytriazinyl-substituted difluoromethanesulfonylanilines | BAYER CROPSCIENCE AG | 2011-09-14 | — | — | CN | disclosed |
| EP-2320735-A2 | HERBICIDAL COMBINATION WITH DIMETHOXY-TRIAZINYL-SUBSTITUTED DIFLUOROMETHANE SULFONYLANILIDES | Bayer CropScience AG (DE) | 2011-05-18 | — | — | EP | disclosed |
| EP-2320735-A2 | HERBICIDAL COMBINATION WITH DIMETHOXY-TRIAZINYL-SUBSTITUTED DIFLUOROMETHANE SULFONYLANILIDES | Bayer CropScience AG (DE) | 2011-05-18 | — | — | EP | disclosed |
| US-20110092368-A1 | 2,4,6-Phenyl-substituted cyclic ketoenols | FISCHER REINER | 2011-04-21 | — | — | US | disclosed |
| US-20110092368-A1 | 2,4,6-Phenyl-substituted cyclic ketoenols | FISCHER REINER | 2011-04-21 | — | — | US | disclosed |
| US-7888285-B2 | 2,4,6-phenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-02-15 | — | — | US | disclosed |
| US-7888285-B2 | 2,4,6-phenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-02-15 | — | — | US | disclosed |
| WO-2010017923-A2 | HERBICIDAL COMBINATION WITH DIMETHOXY-TRIAZINYL-SUBSTITUTED DIFLUOROMETHANE SULFONYLANILIDES | BAYER CROPSCIENCE AG (DE) | 2010-02-18 | — | — | WO | disclosed |
| WO-2009053053-A2 | HERBICIDAL COMBINATION | BAYER CROPSCIENCE AG (DE) | 2009-04-30 | — | — | WO | disclosed |
| WO-2009053053-A2 | HERBICIDAL COMBINATION | BAYER CROPSCIENCE AG (DE) | 2009-04-30 | — | — | WO | disclosed |
| WO-2008138551-A2 | 3-(2-ALKOXY-PHENYL)-SUBSTITUTED TETRAMATES | BAYER CROPSCIENCE AG (DE) | 2008-11-20 | — | — | WO | disclosed |
| EP-1992614-A1 | 3-(2-Alkoxy-phenyl)-substituted tetramates | Bayer CropScience Aktiengesellschaft (DE) | 2008-11-19 | — | — | EP | disclosed |
| US-20070015664-A1 | 2,4,6-Phenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2007-01-18 | — | — | US | disclosed |
| US-20070015664-A1 | 2,4,6-Phenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2007-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070015664-A1 | 2,4,6-Phenyl substituted cyclic ketoenols | CYP4X1, KDM4E, KCNE1 | GSK3B 138/4885CDK4 458/4885CCND1 781/4885 |
| US-20110092368-A1 | 2,4,6-Phenyl-substituted cyclic ketoenols | CYP4X1, KDM4E, PDHX | GSK3B 201/4885CDK4 432/4885CCND1 777/4885 |
| US-20100093542-A1 | HERBICIDE COMBINATION COMPRISING DIMETHOXYTRIAZINYL SUBSTITUTED DIFLUOROMETHANESULFONYLANILIDES | DDT, B2M, THRB | GSK3B 1941/4885CDK4 749/4885CCND1 670/4885 |
| US-20100304971-A1 | HERBICIDAL COMBINATION | DDT, AADAC, CYP1B1 | GSK3B 2155/4885CDK4 449/4885CCND1 2068/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.