Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 3/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14080893 | 0.77 | GAA (0.45) | KMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL14080978 | 0.77 | GAA (0.45) | KMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL12021175 | 0.73 | BRD4 (0.43) | KMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL18425663 | 0.73 | CACNA1G (0.50) | HPGDTSHRGRM2 | |
| SCHEMBL397692 | 0.71 | SMN1; SMN2 (0.45) | KMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL14815101 | 0.70 | KDM4E (0.61) | KMT2ASMN1; SMN2HPGDTSHRHDAC6 | |
| SCHEMBL14815215 | 0.70 | KDM4E (0.61) | KMT2ASMN1; SMN2HPGDTSHRHDAC6 | |
| SCHEMBL14833436 | 0.70 | KDM4E (0.61) | KMT2ASMN1; SMN2HPGDTSHRHDAC6 | |
| SCHEMBL30337582 | 0.70 | SMN1; SMN2 (0.45) | KMT2ASMN1; SMN2HPGDTSHR | |
| SCHEMBL14833231 | 0.70 | KDM4E (0.61) | KMT2ASMN1; SMN2HPGDTSHRHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598253-B2 | Reverse-turn mimetics and methods relating thereto | MYRIAD GENETICS, INC. (US) | 2009-10-06 | — | — | US | disclosed |
| US-7598253-B2 | Reverse-turn mimetics and methods relating thereto | MYRIAD GENETICS, INC. (US) | 2009-10-06 | — | — | US | disclosed |