Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14815215 | 1.00 | KDM4E (0.61) | KDM4EL3MBTL1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL14833231 | 1.00 | KDM4E (0.61) | KDM4EL3MBTL1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL14815101 | 1.00 | KDM4E (0.61) | KDM4EL3MBTL1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL30337582 | 0.76 | SMN1; SMN2 (0.45) | L3MBTL1KMT2ASMN1; SMN2HPGDTSHR | |
| SCHEMBL31435145 | 0.75 | THRB (0.55) | THRB | |
| SCHEMBL4555734 | 0.74 | THRB (0.60) | THRB | |
| SCHEMBL30337144 | 0.72 | SLC6A2 (0.44) | L3MBTL1KMT2ASMN1; SMN2POLBCYP2D6 | |
| SCHEMBL30337246 | 0.71 | ENPP2 (0.47) | L3MBTL1KMT2ASMN1; SMN2CYP2D6THRB | |
| SCHEMBL13673303 | 0.70 | KMT2A (0.52) | KMT2AMEN1SMN1; SMN2HPGDTSHR | |
| SCHEMBL31190825 | 0.70 | HPGD (0.64) | KMT2ASMN1; SMN2HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109251211-B | Quinolone carboxylic acid compound and intermediate thereof, preparation method and application | 广东省中医院（广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院） | 2025-03-07 | — | — | CN | disclosed |
| WO-2013049174-A1 | SUBSTITUTED OCTAHYDROPYRROLO[1,2-A]PYRAZINE SULFONAMIDES AS CALCIUM CHANNEL BLOCKERS | ABBVIE INC. (US) | 2013-04-04 | — | — | WO | disclosed |