Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.45 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.45 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14080978 | 1.00 | GAA (0.45) | GAAHTTSMN1; SMN2MAPK1CACNA1G | |
| SCHEMBL13673303 | 0.77 | KMT2A (0.52) | SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL18425663 | 0.72 | CACNA1G (0.50) | CACNA1GCACNA1HCACNA1I | |
| SCHEMBL10159083 | 0.71 | KMT2A (0.59) | GAAHTTSMN1; SMN2MAPK1MEN1 | |
| SCHEMBL12205992 | 0.67 | ALDH1A1 (0.58) | GAAHTTSMN1; SMN2MAPK1MEN1 | |
| SCHEMBL13484174 | 0.67 | HPGD (0.47) | CACNA1GCACNA1HCACNA1IMEN1KMT2A | |
| SCHEMBL9766998 | 0.66 | HPGD (0.46) | CACNA1GCACNA1HCACNA1IMEN1KMT2A | |
| SCHEMBL21262206 | 0.65 | TSHR (0.47) | SMN1; SMN2CACNA1GCACNA1HCACNA1IKMT2A | |
| SCHEMBL9771398 | 0.65 | ADORA2A (0.48) | SMN1; SMN2MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL9771335 | 0.65 | ADORA2A (0.48) | SMN1; SMN2MEN1KMT2AL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7407952-B2 | Reverse-turn mimetics and compositions and methods related thereto | MYRIAD GENETICS, INC. (US) | 2008-08-05 | — | — | US | disclosed |
| US-7407952-B2 | Reverse-turn mimetics and compositions and methods related thereto | MYRIAD GENETICS, INC. (US) | 2008-08-05 | — | — | US | disclosed |