SCHEMBL13674375

SCHEMBL13674375

Cc1ccc(Sc2ccc(C(=O)c3ccc4ccccc4c3)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.50
RAB9A P51151 4/20 0.50
ALDH1A1 P00352 3/20 0.50
LMNA P02545 1/20 0.50
ACHE P22303 1/20 0.50
HSD17B14 Q9BPX1 1/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
CES2 O00748 1/20 0.49
CES1 P23141 1/20 0.49
HPGD P15428 2/20 0.47
MAPT P10636 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
CLK1 P49759 1/20 0.45
DYRK1A Q13627 1/20 0.45
DYRK1B Q9Y463 1/20 0.45
SRD5A2 P31213 1/20 0.44
CYP2A6 P11509 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
KAT6A Q92794 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15040985 0.90 ALDH1A1 (0.61) NPC1RAB9AALDH1A1LMNAACHE
Benzophenone SCHEMBL8073831 0.83 ALDH1A1 (0.61) NPC1RAB9AALDH1A1LMNAMEN1
SCHEMBL51730 0.83 ALDH1A1 (0.61) NPC1RAB9AALDH1A1LMNAMEN1
SCHEMBL4110575 0.83 ALDH1A1 (0.63) NPC1RAB9AALDH1A1LMNAMEN1
SCHEMBL13674564 0.83 ALDH1A1 (0.63) NPC1RAB9AALDH1A1LMNAMEN1
SCHEMBL25367336 0.83 HSD17B14 (0.48) NPC1RAB9AALDH1A1ACHEHSD17B14
SCHEMBL21230327 0.83 ALDH1A1 (0.73) NPC1RAB9AALDH1A1LMNAACHE
SCHEMBL14571023 0.83 ALDH1A1 (0.73) RAB9AALDH1A1LMNAMEN1KMT2A
SCHEMBL6427029 0.83 ALDH1A1 (0.73) RAB9AALDH1A1LMNAMEN1KMT2A
SCHEMBL2152353 0.82 ACHE (0.54) NPC1RAB9AALDH1A1ACHEHSD17B14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1395615-B1 OXIME ESTER PHOTOINITIATORS HAVING A COMBINED STRUCTURE BASF SE (DE) 2009-10-21 EP disclosed
US-7189489-B2 Oxime ester photoiniators having a combined structure CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-03-13 US disclosed
US-7189489-B2 Oxime ester photoiniators having a combined structure CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-03-13 US disclosed