⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29044901 | 0.87 | ALDH1A1 (0.46) | — | |
| SCHEMBL729438 | 0.87 | TSHR (0.39) | — | |
| SCHEMBL8435307 | 0.84 | — | — | |
| SCHEMBL28105324 | 0.81 | TSHR (0.50) | — | |
| SCHEMBL199633 | 0.81 | — | — | |
| SCHEMBL17350422 | 0.80 | — | — | |
| SCHEMBL2822791 | 0.78 | — | — | |
| SCHEMBL2333903 | 0.75 | HSD17B10 (0.32) | — | |
| SCHEMBL8885919 | 0.75 | THRB (0.35) | — | |
| SCHEMBL29268386 | 0.75 | LMNA (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110286777-A1 | LUBRICANT AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING SAME | RICOH COMPANY, LTD. (JP) | 2011-11-24 | — | — | US | disclosed |
| US-4110117-A | Coating composition | MOBIL OIL CORPORATION (US) | 1978-08-29 | — | — | US | disclosed |