Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4496265 | 0.89 | F10 (0.56) | F10 | |
| SCHEMBL13675127 | 0.84 | F10 (0.44) | F10 | |
| SCHEMBL13674875 | 0.84 | F10 (0.44) | F10 | |
| SCHEMBL13672293 | 0.82 | F10 (0.53) | F10 | |
| SCHEMBL4492159 | 0.82 | F10 (0.53) | F10 | |
| SCHEMBL4492161 | 0.82 | F10 (0.53) | F10 | |
| SCHEMBL13674870 | 0.81 | F10 (0.62) | F10 | |
| SCHEMBL4961883 | 0.78 | F10 (0.70) | F10 | |
| SCHEMBL13675120 | 0.77 | CYP1A2 (0.45) | F10CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL13675148 | 0.75 | F10 (0.44) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7601752-B2 | Pyrrolidine derivatives | HOFFMANN-LA ROCHE INC. (US) | 2009-10-13 | — | — | US | disclosed |