Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13674875 | 0.80 | F10 (0.44) | F10 | |
| SCHEMBL13675127 | 0.80 | F10 (0.44) | F10 | |
| SCHEMBL13672297 | 0.79 | F10 (0.54) | F10 | |
| SCHEMBL13675147 | 0.78 | F10 (0.41) | F10 | |
| Trifluoroacetic Acid SCHEMBL4477007 | 0.76 | F10 (0.52) | F10 | |
| SCHEMBL13675146 | 0.75 | F10 (0.45) | F10 | |
| SCHEMBL13726768 | 0.73 | F10 (0.58) | F10 | |
| SCHEMBL4638999 | 0.73 | ABCC9 (0.44) | F10 | |
| SCHEMBL85048 | 0.69 | F10 (0.48) | F10 | |
| SCHEMBL3544845 | 0.68 | F10 (0.54) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7601752-B2 | Pyrrolidine derivatives | HOFFMANN-LA ROCHE INC. (US) | 2009-10-13 | — | — | US | disclosed |