Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.54 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | MPO | P05164 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6897550 | 0.80 | GAA (0.52) | ANPEPERAP2ADRB2SIGMAR1GAA | |
| Hydrochloric Acid SCHEMBL6897545 | 0.80 | GAA (0.52) | ANPEPERAP2ADRB2SIGMAR1GAA | |
| SCHEMBL10676903 | 0.79 | ADRB2 (0.51) | ANPEPERAP2ADRB2SIGMAR1GAA | |
| SCHEMBL5226075 | 0.77 | SIGMAR1 (0.61) | SIGMAR1GAAMAPTKCNH2MPO | |
| SCHEMBL31122408 | 0.77 | ADRB2 (0.53) | ANPEPERAP2ADRB2SIGMAR1GAA | |
| SCHEMBL283735 | 0.76 | SIGMAR1 (0.81) | SIGMAR1GAAMAPTKCNH2NPC1 | |
| SCHEMBL25343744 | 0.76 | MEN1 (0.52) | ANPEPGAAMAPT | |
| SCHEMBL13416723 | 0.76 | ALDH1A1 (0.56) | ANPEPERAP2ADRB2SIGMAR1GAA | |
| SCHEMBL9662196 | 0.76 | KCNH2 (0.69) | ANPEPERAP2ADRB2SIGMAR1GAA | |
| SCHEMBL10720145 | 0.76 | ADRB2 (0.77) | ADRB2GAAKCNH2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598253-B2 | Reverse-turn mimetics and methods relating thereto | MYRIAD GENETICS, INC. (US) | 2009-10-06 | — | — | US | disclosed |