Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.55 |
| ▸ | BCR | P11274 | 2/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 2/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 2/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7765101 | 0.86 | ABL1 (0.51) | ABL1ABCB1BCRHDAC4HDAC2 | |
| SCHEMBL9959026 | 0.84 | ABL1 (0.46) | ABL1ABCB1BCRHDAC4HDAC2 | |
| SCHEMBL13675365 | 0.83 | ABL1 (0.56) | ABL1ABCB1BCRHDAC4HDAC2 | |
| SCHEMBL1520607 | 0.83 | ABL1 (0.56) | ABL1ABCB1BCRHDAC4HDAC2 | |
| SCHEMBL28792762 | 0.81 | ABL1 (0.55) | ABL1ABCB1BCRHDAC4HDAC2 | |
| SCHEMBL10821571 | 0.81 | ABL1 (0.55) | ABL1ABCB1BCRHDAC4HDAC2 | |
| SCHEMBL3756401 | 0.81 | DPP4 (0.62) | ABL1ABCB1BCRHDAC4HDAC2 | |
| SCHEMBL5677687 | 0.81 | TP53 (0.53) | ABL1ABCB1BCRHDAC4HDAC2 | |
| Hydrochloric Acid SCHEMBL12490497 | 0.80 | DPP4 (0.60) | ABL1ABCB1BCRHDAC4HDAC2 | |
| SCHEMBL4375331 | 0.80 | PPARA (0.53) | ABL1ABCB1BCRHDAC4HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885236-A1 | OLIGONUCLEOTIDE ANALOGS | Codon Pharmaceuticals, Inc. (US) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997027206-A1 | OLIGONUCLEOTIDE ANALOGS | CODON PHARMACEUTICALS, INC. (US) | 1997-07-31 | — | — | WO | disclosed |