Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 17/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.48 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.48 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.48 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10288974 | 0.91 | SIGMAR1 (0.62) | SIGMAR1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL13060706 | 0.83 | SIGMAR1 (0.50) | SIGMAR1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL13060701 | 0.83 | SIGMAR1 (0.50) | SIGMAR1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL792219 | 0.83 | SIGMAR1 (0.71) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8694185 | 0.82 | SIGMAR1 (0.69) | SIGMAR1 | |
| SCHEMBL13306955 | 0.82 | SIGMAR1 (0.73) | SIGMAR1 | |
| SCHEMBL13061122 | 0.78 | CXCR4 (0.60) | SIGMAR1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10288526 | 0.77 | SIGMAR1 (0.60) | SIGMAR1KDM4ETSHR | |
| SCHEMBL1901538 | 0.77 | HRH3 (0.70) | SIGMAR1KDM4EALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL18516616 | 0.77 | SIGMAR1 (0.62) | SIGMAR1KDM4EALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090270381-A1 | Non-steroidal progesterone receptor modulators | BAYER SCHERING PHARMA AG (DE) | 2009-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270381-A1 | Non-steroidal progesterone receptor modulators | PGR, PGRMC1, PGRMC2 | SIGMAR1 120/4885KDM4E 992/4885ALDH1A1 1257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.