Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | TP53 | P04637 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13675806 | 1.00 | MAPT (0.50) | MAPTTP53KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7438162 | 0.84 | ALDH1A1 (0.54) | MAPTTP53KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL431571 | 0.78 | NPBWR1 (0.54) | MAPTTP53KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7438151 | 0.77 | MAPT (0.50) | MAPTTP53KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL29157145 | 0.77 | SMN1; SMN2 (0.52) | MAPTTP53KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11782973 | 0.77 | MAPT (0.56) | MAPTTP53KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL15218725 | 0.76 | ALDH1A1 (0.53) | MAPTTP53KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL12536011 | 0.75 | ALDH1A1 (0.50) | MAPTKMT2AMEN1SMN1; SMN2CYP3A4 | |
| SCHEMBL5995430 | 0.75 | CNR1 (0.45) | KMT2AMEN1SMN1; SMN2CYP2C19LMNA | |
| SCHEMBL5512074 | 0.75 | MAPT (0.52) | MAPTTP53KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7601842-B2 | Method for producing an optically active tetrahydroquinoline | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-10-13 | — | — | US | disclosed |