Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | MLNR | O43193 | 5/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13674425 | 0.90 | HSD11B1 (0.42) | HSD11B1BRD4MLNRITGB3ITGA2B | |
| SCHEMBL13674483 | 0.78 | ALDH1A1 (0.33) | HSD11B1BRD4MLNRL3MBTL1KMT2A | |
| SCHEMBL4507389 | 0.76 | HSD11B1 (0.49) | HSD11B1MLNRITGB3ITGA2BL3MBTL1 | |
| SCHEMBL4525978 | 0.76 | HSD11B1 (0.46) | HSD11B1MLNRITGB3ITGA2BL3MBTL1 | |
| SCHEMBL3545737 | 0.74 | HSD11B1 (0.67) | HSD11B1TP53KMT2AALDH1A1 | |
| SCHEMBL4524837 | 0.74 | HSD11B1 (0.44) | HSD11B1KMT2AALDH1A1 | |
| SCHEMBL13674466 | 0.73 | KDM4E (0.39) | BRD4KMT2ACREBBPALDH1A1 | |
| SCHEMBL4509889 | 0.72 | HSD11B1 (0.51) | HSD11B1TP53L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL2990527 | 0.72 | HSD11B1 (0.42) | HSD11B1TP53FPR2ALDH1A1 | |
| SCHEMBL4517944 | 0.71 | HSD11B1 (0.56) | HSD11B1TP53KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090264650-A1 | Prophylactic/Therapeutic Agent for Diabetes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264650-A1 | Prophylactic/Therapeutic Agent for Diabetes | HSD11B1, HSD17B1, HSD11B2 | HSD11B1 1/4885BRD4 3776/4885MLNR 4149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.