Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | NMT1 | P30419 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13675539 | 1.00 | CA1 (0.42) | CA1CA12MMP8MAPTPOLB | |
| SCHEMBL13675805 | 0.79 | ALDH1A1 (0.47) | CA1CA12MMP8MAPTPOLB | |
| SCHEMBL13675809 | 0.79 | ALDH1A1 (0.47) | CA1CA12MMP8MAPTPOLB | |
| SCHEMBL13675804 | 0.76 | CA1 (0.41) | CA1CA12MMP8MAPTPOLB | |
| SCHEMBL13675810 | 0.76 | CA1 (0.41) | CA1CA12MMP8MAPTPOLB | |
| SCHEMBL2629438 | 0.76 | CA12 (0.38) | CA1CA12MMP8MAPTPOLB | |
| SCHEMBL13675544 | 0.73 | MAPT (0.50) | CA1CA12MMP8MAPTPOLB | |
| SCHEMBL13675806 | 0.73 | MAPT (0.50) | CA1CA12MMP8MAPTPOLB | |
| SCHEMBL28029795 | 0.72 | CA1 (0.47) | CA1CA12MMP8MAPTPOLB | |
| SCHEMBL3628968 | 0.67 | CYP2A6 (0.38) | MAPTMEN1LMNAKMT2ACYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7601842-B2 | Method for producing an optically active tetrahydroquinoline | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-10-13 | — | — | US | disclosed |