Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 5/20 | 0.48 |
| ▸ | PTGDR | Q13258 | 5/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | CCKAR | P32238 | 1/20 | 0.42 |
| ▸ | USP14 | P54578 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13841442 | 1.00 | PTGDR2 (0.48) | PTGDR2TBXA2RPTGDRHSD17B10ABCB11 | |
| SCHEMBL833419 | 0.91 | PTGDR2 (0.58) | PTGDR2TBXA2RPTGDRHSD17B10ABCB11 | |
| SCHEMBL833418 | 0.91 | PTGDR2 (0.58) | PTGDR2TBXA2RPTGDRHSD17B10ABCB11 | |
| SCHEMBL13841441 | 0.84 | PTGDR2 (0.54) | PTGDR2TBXA2RPTGDRHSD17B10ABCB11 | |
| SCHEMBL21754353 | 0.81 | USP14 (0.42) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| SCHEMBL13677407 | 0.80 | PTGDR2 (0.52) | PTGDR2TBXA2RPTGDRHSD17B10ABCB11 | |
| SCHEMBL833095 | 0.79 | PTGDR2 (0.58) | PTGDR2TBXA2RPTGDRHSD17B10ABCB11 | |
| SCHEMBL2427080 | 0.78 | KDM4E (0.50) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| SCHEMBL832476 | 0.78 | KMT2A (0.41) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| SCHEMBL832475 | 0.78 | KMT2A (0.41) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090258922-A1 | COMPOUND EXHIBITING PGD2 RECEPTOR ANTAGONIST | SHIONOGI & CO., LTD. | 2009-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258922-A1 | COMPOUND EXHIBITING PGD2 RECEPTOR ANTAGONIST | CYSLTR2, CYSLTR1, HRH2 | PTGDR2 7/4885TBXA2R 18/4885PTGDR 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.