Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 11/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.32 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4076105 | 0.84 | KDM4C (0.41) | KDM4CMEN1KMT2ANPC1RAB9A | |
| SCHEMBL4250862 | 0.81 | MAPK14 (0.49) | MAPK14MAPK9CDK8MAPK12MAPK11 | |
| SCHEMBL4139540 | 0.78 | MEN1 (0.40) | KDM4CMEN1KMT2ANPC1RAB9A | |
| SCHEMBL16398841 | 0.78 | GAA (0.44) | MAPK14MAPK9CDK8MAPK12MAPK11 | |
| SCHEMBL4505212 | 0.78 | MAPK14 (0.48) | MAPK14MAPK9CDK8MAPK12MAPK11 | |
| SCHEMBL16278814 | 0.77 | KDM4C (0.39) | KDM4CMEN1KMT2ANPC1RAB9A | |
| SCHEMBL4076188 | 0.76 | KDM4C (0.42) | KDM4CMEN1KMT2ANPC1RAB9A | |
| SCHEMBL15006786 | 0.76 | GAA (0.42) | MEN1KMT2AMAPK14MAPK9CDK8 | |
| SCHEMBL4078729 | 0.76 | KDM4C (0.39) | KDM4CMEN1KMT2ANPC1RAB9A | |
| SCHEMBL16279038 | 0.75 | ALDH1A1 (0.45) | KDM4CMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090270350-A1 | Pyridinone Pyrazole Urea and Pyrimidinone Pyrazole Urea Derivatives | PFIZER INC. | 2009-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270350-A1 | Pyridinone Pyrazole Urea and Pyrimidinone Pyrazole Urea Derivatives | PDXK, UMPS, CDK2 | KDM4C 1262/4885MEN1 4558/4885KMT2A 2604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.