Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1030623 | 0.83 | GABRR1 (0.39) | ALDH1A1LMNAPOLBGABRR1 | |
| SCHEMBL8413192 | 0.83 | GABRR1 (0.39) | ALDH1A1LMNAPOLBGABRR1 | |
| SCHEMBL1030281 | 0.83 | GABRR1 (0.39) | ALDH1A1LMNAPOLBGABRR1 | |
| SCHEMBL1030622 | 0.83 | GABRR1 (0.39) | ALDH1A1LMNAPOLBGABRR1 | |
| SCHEMBL17756079 | 0.77 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL13678758 | 0.75 | EPHX1 (0.31) | — | |
| SCHEMBL7273731 | 0.74 | POLB (0.39) | ALDH1A1LMNAPOLBGABRR1 | |
| SCHEMBL7280473 | 0.74 | POLB (0.39) | ALDH1A1LMNAPOLBGABRR1 | |
| SCHEMBL1933031 | 0.74 | POLB (0.39) | ALDH1A1LMNAPOLBGABRR1 | |
| SCHEMBL7325402 | 0.74 | POLB (0.39) | ALDH1A1LMNAPOLBGABRR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160137639-A1 | TRIAZOLE-ISOXAZOLE COMPOUND AND MEDICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2016-05-19 | — | — | US | disclosed |
| US-20090270360-A1 | DICARBOXAMIDE DERIVATIVES | BOEHRINGER MARKUS | 2009-10-29 | — | — | US | disclosed |
| US-7501413-B2 | Dicarboxamide derivatives | HOFFMANN-LA ROCHE INC. (US) | 2009-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270360-A1 | DICARBOXAMIDE DERIVATIVES | F2, F12, TFPI | ALDH1A1 1180/4885LMNA 1057/4885POLB 3769/4885 |
| US-20160137639-A1 | TRIAZOLE-ISOXAZOLE COMPOUND AND MEDICAL USE THEREOF | CYP3A7, CYP2C19, CYP3A5 | ALDH1A1 560/4885LMNA 4195/4885POLB 3827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.