Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13091213 | 0.86 | SRC (0.44) | NPC1RAB9ASRCMEN1KMT2A | |
| SCHEMBL21894227 | 0.83 | TAAR1 (0.49) | TAAR1NPC1RAB9ASRCMEN1 | |
| SCHEMBL705718 | 0.78 | CTBP2 (0.50) | TAAR1NPC1MEN1KMT2APOLB | |
| SCHEMBL29375293 | 0.77 | SRC (0.58) | TAAR1NPC1RAB9ASRCSLC22A12 | |
| SCHEMBL37138 | 0.77 | SRC (0.58) | TAAR1NPC1RAB9ASRCSLC22A12 | |
| SCHEMBL9969945 | 0.77 | TAAR1 (0.48) | TAAR1NPC1RAB9ASRCSLC22A12 | |
| SCHEMBL1259688 | 0.77 | TAAR1 (0.48) | TAAR1NPC1RAB9ASRCSLC22A12 | |
| SCHEMBL1171323 | 0.76 | ALDH1A1 (0.35) | SRCTGM2HPGDALDH1A1TSHR | |
| SCHEMBL37438 | 0.76 | TAAR1 (0.47) | TAAR1NPC1RAB9ASRCSLC22A12 | |
| SCHEMBL30570712 | 0.76 | TAAR1 (0.52) | TAAR1NPC1RAB9ASRCSLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1411046-B1 | QUINOLINE DERIVATIVE AND QUINAZOLINE DERIVATIVE INHIBITING SELF-PHOSPHORYLATION OF HEPATOCYTUS PROLIFERATOR RECEPTOR, AND MEDICINAL COMPOSITION CONTAINING THE SAME | KIRIN PHARMA KK (JP) | 2009-09-16 | — | — | EP | disclosed |