SCHEMBL37438

SCHEMBL37438

Cc1ccc(C)c(CC(=O)Cl)c1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.47
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
GAA P10253 2/20 0.41
SLC22A12 Q96S37 1/20 0.40
POLB P06746 1/20 0.40
HTT P42858 2/20 0.40
SRC P12931 1/20 0.40
ALDH1A1 P00352 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
PTGS2 P35354 3/20 0.39
KDM4E B2RXH2 1/20 0.39
KDM4C Q9H3R0 1/20 0.39
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29606577 1.00 TAAR1 (0.47) TAAR1NPC1RAB9AMEN1KMT2A
SCHEMBL30570712 0.84 TAAR1 (0.52) TAAR1NPC1RAB9AMEN1KMT2A
SCHEMBL2530247 0.84 P2RX7 (0.44) TAAR1NPC1RAB9AMEN1KMT2A
SCHEMBL1478491 0.84 TAAR1 (0.52) TAAR1NPC1RAB9AMEN1KMT2A
SCHEMBL27681376 0.82 FFAR1 (0.45) NPC1RAB9AMEN1KMT2APOLB
SCHEMBL1259688 0.82 TAAR1 (0.48) TAAR1NPC1RAB9AMEN1KMT2A
SCHEMBL29375293 0.82 SRC (0.58) TAAR1NPC1RAB9AMEN1KMT2A
SCHEMBL9969945 0.82 TAAR1 (0.48) TAAR1NPC1RAB9AMEN1KMT2A
SCHEMBL37138 0.82 SRC (0.58) TAAR1NPC1RAB9AMEN1KMT2A
SCHEMBL6036617 0.81 PTGS2 (0.40) TAAR1NPC1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12612359-B2 Cis-para-substituted cyclohexylaminonitrile salt, preparation method therefor and use thereof, and method for preparing pesticide using same Lansheng Biotechnology Group Co., Ltd. (CN) 2026-04-28 US claimed
CN-117209448-A Process for the preparation of (benzo) thiazole-containing thio/selenoacetamides and derivatives thereof 济宁医学院 2023-12-12 CN claimed
CN-117126119-A Preparation method of (benzo) thiazole amide-containing compound 济宁医学院 2023-11-28 CN claimed
EP-4234533-A1 CIS-PARA-SUBSTITUTED CYCLOHEXYLAMINONITRILE SALT, PREPARATION METHOD THEREFOR AND USE THEREOF, AND METHOD FOR PREPARING PESTICIDE USING SAME Hebei Lansheng Biotech Co., Ltd (CN) 2023-08-30 EP claimed
US-20230257341-A1 CIS-PARA-SUBSTITUTED CYCLOHEXYLAMINONITRILE SALT, PREPARATION METHOD THEREFOR AND USE THEREOF, AND METHOD FOR PREPARING PESTICIDE USING SAME HEBEI LANSHENG BIOTECH CO., LTD (CN) 2023-08-17 US claimed
CN-115448869-A Preparation method of intermediate for synthesizing spirotetramat 顺毅南通化工有限公司 2022-12-09 CN claimed
CN-112341362-B Cis-para-substituted cyclohexyl amino nitrile malate, and preparation and application thereof 永农生物科学有限公司 2022-08-02 CN claimed
WO-2022083494-A1 CIS-PARA-SUBSTITUTED CYCLOHEXYLAMINONITRILE SALT, PREPARATION METHOD THEREFOR AND USE THEREOF, AND METHOD FOR PREPARING PESTICIDE USING SAME 河北兰升生物科技有限公司 2022-04-28 WO claimed
CN-108797142-B Preparation method of moisture-absorbing, antibacterial and water vapor permeable graphene modified polyurethane synthetic leather 浙江英飞实业有限公司 2021-09-21 CN claimed
EP-3819289-A1 CIS-PARA-SUBSTITUTED CYCLOHEXYLAMINO NITRILE SALT AND PREPARATION METHOD THEREFOR Hebei Lansheng Biotech Co., Ltd (CN) 2021-05-12 EP claimed
CN-108468225-B Preparation method of polyurethane synthetic leather with good moisture absorption, air permeability and water vapor permeability 三明建华纺织有限公司 2021-04-20 CN claimed
CN-112341362-A Cis-para-substituted cyclohexyl amino nitrile malate, and preparation and application thereof 永农生物科学有限公司 2021-02-09 CN claimed
CN-110691771-B Cis-para-substituted cyclohexyl amino nitrile salt and preparation method thereof 河北兰升生物科技有限公司 2020-10-09 CN claimed
CN-111072470-A Method for preparing 2, 5-dimethyl phenylacetyl chloride 大连奇凯医药科技有限公司 2020-04-28 CN claimed
CN-109369378-B Synthetic method of insecticide spirotetramat intermediate 2, 5-dimethyl phenylacetyl chloride 山东省农药科学研究院 2020-02-18 CN claimed
CN-110691771-A Cis-para-substituted cyclohexyl amino nitrile salt and preparation method thereof 河北兰升生物科技有限公司 2020-01-14 CN claimed
WO-2019233498-A1 CIS-PARA-SUBSTITUTED CYCLOHEXYLAMINO NITRILE SALT AND PREPARATION METHOD THEREFOR 河北兰升生物科技有限公司 (CN) 2019-12-12 WO claimed
US-12612359-B2 Cis-para-substituted cyclohexylaminonitrile salt, preparation method therefor and use thereof, and method for preparing pesticide using same Lansheng Biotechnology Group Co., Ltd. (CN) 2026-04-28 US disclosed
US-20020010204-A1 2- and 2,5-substituted phenylketoenols LIEB FOLKER (DE) 2002-01-24 US disclosed
US-6255342-B1 PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2001-07-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230257341-A1 CIS-PARA-SUBSTITUTED CYCLOHEXYLAMINONITRILE SALT, PREPARATION METHOD THEREFOR AND USE THEREOF, AND METHOD FOR PREPARING PESTICIDE USING SAME CYP4F11, CYP4A11, NOTUM TAAR1 2832/4885NPC1 785/4885RAB9A 793/4885
US-12612359-B2 Cis-para-substituted cyclohexylaminonitrile salt, preparation method therefor and use thereof, and method for preparing pesticide using same SLC6A11, CA2, CYP4F11 TAAR1 2467/4885NPC1 2281/4885RAB9A 3005/4885
US-20020010204-A1 2- and 2,5-substituted phenylketoenols CYP1B1, CYP4X1, CYP1A1 TAAR1 2753/4885NPC1 2728/4885RAB9A 4605/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.