Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | NPC1 | O15118 | 3/20 | 0.70 |
| ▸ | RAB9A | P51151 | 3/20 | 0.70 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | LDLR | P01130 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13679615 | 0.88 | MEN1 (0.70) | MEN1KMT2ANPC1RAB9AHTT | |
| SCHEMBL13679559 | 0.82 | MEN1 (0.78) | MEN1KMT2ANPC1RAB9AHTT | |
| SCHEMBL13679713 | 0.76 | TP53 (0.62) | MEN1KMT2ANPC1RAB9AHTT | |
| SCHEMBL14642446 | 0.74 | TP53 (0.60) | MEN1KMT2AHTTKDM4EALDH1A1 | |
| SCHEMBL14642400 | 0.73 | TP53 (0.62) | MEN1KMT2AHTTKDM4EALDH1A1 | |
| SCHEMBL1336773 | 0.73 | SMO (0.59) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL13679598 | 0.73 | TP53 (0.61) | MEN1KMT2ANPC1RAB9AHTT | |
| SCHEMBL13679613 | 0.73 | TP53 (0.64) | MEN1KMT2AHTTKDM4EALDH1A1 | |
| SCHEMBL13679606 | 0.72 | MAPT (0.66) | MEN1KMT2ANPC1KDM4EALDH1A1 | |
| SCHEMBL13679620 | 0.72 | LDLR (0.65) | NPC1RAB9AKDM4EALDH1A1LDLR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1482928-B1 | MEDIATORS OF HEDGEHOG SIGNALING PATHWAYS,COMPOSITIONS AND USES RELATED THERETO | CURIS INC (US) | 2009-09-23 | — | — | EP | disclosed |