Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GLA | P06280 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | SELP | P16109 | 2/20 | 0.41 |
| ▸ | SELE | P16581 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13679702 | 0.91 | PTPN1 (0.72) | NOX1PTPN1ALOX5KDM4EALDH1A1 | |
| SCHEMBL8797319 | 0.91 | PTPN1 (0.72) | NOX1PTPN1ALOX5KDM4EALDH1A1 | |
| SCHEMBL13679657 | 0.89 | NOX1 (0.60) | NOX1PTPN1ALOX5KDM4EALDH1A1 | |
| SCHEMBL6606552 | 0.85 | NOX1 (0.57) | NOX1PTPN1ALOX5KDM4EALDH1A1 | |
| SCHEMBL6608693 | 0.82 | NOX1 (0.62) | NOX1PTPN1ALOX5KDM4EALDH1A1 | |
| SCHEMBL6611375 | 0.81 | NOX1 (0.61) | NOX1PTPN1ALOX5KDM4EALDH1A1 | |
| SCHEMBL6622165 | 0.80 | NOX1 (0.62) | NOX1PTPN1ALOX5MAPTTP53 | |
| SCHEMBL8797410 | 0.79 | NOX1 (0.72) | NOX1PTPN1ALOX5KDM4EALDH1A1 | |
| SCHEMBL13679687 | 0.79 | NOX1 (0.61) | NOX1PTPN1ALOX5MAPTTP53 | |
| SCHEMBL8032578 | 0.78 | NOX1 (0.76) | NOX1PTPN1ALOX5KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0999835-B1 | IMIDAZOLE DERIVATIVES AS MDR MODULATORS | TAIJI BIOMEDICAL INC (US) | 2009-09-09 | — | — | EP | disclosed |