Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MPI | P34949 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3852403 | 0.77 | MAPT (0.59) | MAPTKMT2AGAALMNAPOLB | |
| SCHEMBL3852399 | 0.77 | MAPT (0.59) | MAPTKMT2AGAALMNAPOLB | |
| SCHEMBL5050992 | 0.73 | TSHR (0.76) | MAPTKMT2AGAALMNAPOLB | |
| SCHEMBL2469371 | 0.71 | KMT2A (0.61) | MAPTKMT2ALMNAPOLBKDM4E | |
| SCHEMBL680008 | 0.69 | ALDH1A1 (0.75) | MAPTKMT2AGAALMNAPOLB | |
| SCHEMBL3861001 | 0.68 | MAPT (0.54) | MAPTKMT2AGAALMNAPOLB | |
| SCHEMBL3861002 | 0.68 | MAPT (0.54) | MAPTKMT2AGAALMNAPOLB | |
| SCHEMBL16936153 | 0.68 | GAA (0.56) | MAPTKMT2AGAAKDM4ETSHR | |
| SCHEMBL23400077 | 0.68 | KDM4E (0.63) | MAPTKMT2AGAALMNAPOLB | |
| SCHEMBL28880300 | 0.67 | TSHR (0.81) | MAPTKMT2AGAALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582123-B2 | Coloring composition comprising at least one azomethine compound with a pyrazolinone unit | L'OREAL S.A. (FR) | 2009-09-01 | — | — | US | disclosed |
| US-7582123-B2 | Coloring composition comprising at least one azomethine compound with a pyrazolinone unit | L'OREAL S.A. (FR) | 2009-09-01 | — | — | US | disclosed |