Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Paxamate SCHEMBL2109892 | 0.83 | MEN1 (0.57) | ALDH1A1KDM4ENPC1MAPTHPGD | |
| SCHEMBL13680438 | 0.82 | LMNA (0.67) | MAPTHPGDLMNAPPARGPPARA | |
| Metolcarb SCHEMBL118244 | 0.82 | LMNA (0.65) | ALDH1A1KDM4ENPC1MAPTHPGD | |
| Metolcarb SCHEMBL29413999 | 0.82 | LMNA (0.65) | ALDH1A1KDM4ENPC1MAPTHPGD | |
| SCHEMBL13680495 | 0.81 | MEN1 (0.52) | MAPTLMNAPPARGPPARAGAA | |
| Metolcarb SCHEMBL7079404 | 0.80 | LMNA (0.62) | ALDH1A1KDM4ENPC1MAPTHPGD | |
| Metolcarb SCHEMBL11000289 | 0.80 | LMNA (0.62) | ALDH1A1KDM4ENPC1MAPTHPGD | |
| Metolcarb SCHEMBL28786421 | 0.80 | LMNA (0.62) | ALDH1A1KDM4ENPC1MAPTHPGD | |
| Metolcarb SCHEMBL11681132 | 0.80 | LMNA (0.62) | ALDH1A1KDM4ENPC1MAPTHPGD | |
| Metolcarb SCHEMBL8024716 | 0.80 | LMNA (0.62) | ALDH1A1KDM4ENPC1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |