Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | KIF11 | P52732 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | DHODH | Q02127 | 2/20 | 0.48 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
| ▸ | FLT1 | P17948 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | ICMT | O60725 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680438 | 0.85 | LMNA (0.67) | MEN1KMT2APPARGPPARALMNA | |
| SCHEMBL7647138 | 0.82 | KIF11 (0.59) | MEN1KMT2APPARGPPARAKIF11 | |
| SCHEMBL13680464 | 0.81 | ALDH1A1 (0.48) | MEN1KMT2APPARGPPARALMNA | |
| SCHEMBL13680508 | 0.81 | RAB9A (0.59) | MEN1KMT2APPARGPPARALMNA | |
| SCHEMBL3131557 | 0.81 | LMNA (0.61) | MEN1KMT2AKIF11LMNAGAA | |
| SCHEMBL5700033 | 0.80 | KMT2A (0.73) | MEN1KMT2APPARGLMNAGAA | |
| SCHEMBL27484485 | 0.80 | MEN1 (0.61) | MEN1KMT2ALMNADHODHMAPT | |
| SCHEMBL1955422 | 0.80 | KIF11 (0.61) | MEN1KMT2AKIF11LMNAGAA | |
| SCHEMBL3129703 | 0.80 | LRRK2 (0.48) | MEN1KMT2AKIF11LMNAGAA | |
| SCHEMBL8264168 | 0.80 | PPARG (0.50) | PPARGPPARAGAATDP1ICMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |