Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680525 | 0.84 | RAB9A (0.49) | RAB9ANPC1POLBALDH1A1KDM4E | |
| SCHEMBL13680480 | 0.82 | AOC3 (0.51) | RAB9ANPC1POLBALDH1A1KDM4E | |
| SCHEMBL27759452 | 0.80 | AOC3 (0.52) | RAB9ANPC1POLBALDH1A1KDM4E | |
| SCHEMBL13680526 | 0.80 | RAB9A (0.54) | RAB9ANPC1POLBALDH1A1KDM4E | |
| SCHEMBL13680527 | 0.78 | RAB9A (0.66) | RAB9ANPC1POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL13680939 | 0.77 | MAPT (0.47) | RAB9APOLBALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8198560 | 0.76 | CYP3A4 (0.60) | RAB9ANPC1POLBALDH1A1KDM4E | |
| SCHEMBL13680489 | 0.75 | SMN1; SMN2 (0.47) | RAB9ANPC1POLBALDH1A1KDM4E | |
| SCHEMBL13680523 | 0.75 | RAB9A (0.51) | RAB9ANPC1POLBALDH1A1KDM4E | |
| SCHEMBL2096148 | 0.75 | MAPT (0.61) | RAB9ANPC1POLBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |