Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680525 | 0.86 | RAB9A (0.49) | AOC3PPARAALDH1A1KDM4EHPGD | |
| SCHEMBL13680526 | 0.82 | RAB9A (0.54) | AOC3PPARAALDH1A1KDM4EHPGD | |
| SCHEMBL13680481 | 0.82 | RAB9A (0.49) | AOC3PPARAALDH1A1KDM4EHPGD | |
| SCHEMBL27759452 | 0.82 | AOC3 (0.52) | AOC3PPARAALDH1A1KDM4EHPGD | |
| SCHEMBL13680482 | 0.80 | TGFBR1 (0.51) | AOC3PPARAALDH1A1KDM4ENPC1 | |
| SCHEMBL8198560 | 0.78 | CYP3A4 (0.60) | AOC3ALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL2096148 | 0.77 | MAPT (0.61) | AOC3ALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL7905176 | 0.76 | CYP3A4 (0.58) | AOC3ALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL13680537 | 0.76 | KIF11 (0.54) | PPARAALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL28901237 | 0.74 | AOC3 (0.74) | AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |