Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.51 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23197679 | 0.78 | TDP1 (0.56) | PRMT1GSK3BPTGS2TSHR | |
| SCHEMBL13680560 | 0.77 | GSK3B (0.59) | GSK3BTSHR | |
| SCHEMBL13680516 | 0.76 | CYP1A2 (0.39) | PRMT1SCN10ANPSR1GSK3BP2RX3 | |
| SCHEMBL10222192 | 0.76 | PRMT1 (0.48) | PRMT1NOTUMKIF11GSK3BPTGS2 | |
| SCHEMBL5124585 | 0.75 | ALDH1A1 (0.60) | PRMT1SCN10ANOTUMPRKDC | |
| SCHEMBL22042121 | 0.75 | PRMT1 (0.54) | PRMT1SCN10ANPSR1NOTUMABCB1 | |
| SCHEMBL4606442 | 0.75 | TP53 (0.57) | SCN10ANPSR1NOTUMPRKDCPTGER4 | |
| SCHEMBL5843366 | 0.73 | SCN10A (0.60) | SCN10AABCB1PTGER4 | |
| SCHEMBL1044896 | 0.72 | KIF11 (0.53) | SCN10ANPSR1KIF11NISCHSCN5A | |
| SCHEMBL5539598 | 0.72 | GSK3B (0.57) | GSK3BPTGS2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |