Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 8/20 | 0.60 |
| ▸ | QPCTL | Q9NXS2 | 6/20 | 0.60 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | PRKCI | P41743 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.46 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29804939 | 1.00 | QPCT (0.60) | QPCTQPCTLPSMD11PIK3CAMTOR | |
| SCHEMBL28178020 | 0.84 | PSMD11 (0.64) | QPCTQPCTLPSMD11PIK3CAMTOR | |
| SCHEMBL8634290 | 0.84 | QPCT (0.68) | QPCTQPCTLPSMD11KDM4ENPC1 | |
| SCHEMBL22418756 | 0.83 | QPCT (0.64) | QPCTQPCTLKDM4ENPC1ALDH1A1 | |
| SCHEMBL2462345 | 0.82 | QPCT (0.68) | QPCTQPCTLKDM4ENPC1ALDH1A1 | |
| SCHEMBL484163 | 0.80 | QPCT (0.60) | QPCTQPCTLPSMD11PIK3CAMTOR | |
| SCHEMBL29804755 | 0.80 | QPCT (0.60) | QPCTQPCTLKDM4ENPC1ALDH1A1 | |
| SCHEMBL30612370 | 0.80 | QPCT (0.60) | QPCTQPCTLPSMD11PIK3CAMTOR | |
| SCHEMBL13680531 | 0.80 | QPCT (0.60) | QPCTQPCTLKDM4ENPC1ALDH1A1 | |
| SCHEMBL23227763 | 0.80 | QPCT (0.60) | QPCTQPCTLKDM4ENPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110191882-B | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | 株式会社大熊制药 | 2022-09-13 | — | — | CN | disclosed |
| US-10981917-B2 | Heterocyclic compound, its preparation method, and pharmaceutical composition comprising the same | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2021-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10981917-B2 | Heterocyclic compound, its preparation method, and pharmaceutical composition comprising the same | RNASE1, AARS1, DHPS | QPCT 650/4885QPCTL 499/4885PSMD11 723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.