Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.41 |
| ▸ | ICMT | O60725 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7958069 | 0.79 | ESR1 (0.52) | CLK4DYRK1BHSD17B1HSD17B2 | |
| SCHEMBL6311375 | 0.78 | CYP2A6 (0.60) | ENPP3RAB9AACHEHSD17B1HSD17B2 | |
| SCHEMBL10412952 | 0.77 | CYP1A2 (0.60) | PIN1 | |
| SCHEMBL6561397 | 0.76 | ACHE (0.61) | ENPP3RAB9AFYNCLK4DYRK1B | |
| SCHEMBL31471473 | 0.76 | ACHE (0.69) | ENPP3RAB9AACHEDHODHIDO1 | |
| SCHEMBL301247 | 0.76 | ACHE (0.69) | ENPP3RAB9AACHEDHODHIDO1 | |
| SCHEMBL29373699 | 0.76 | ACHE (0.69) | ENPP3RAB9AACHEDHODHIDO1 | |
| SCHEMBL19577801 | 0.73 | ACHE (0.65) | ENPP3RAB9AACHEDHODHIDO1 | |
| SCHEMBL18797759 | 0.73 | ACHE (0.65) | ENPP3RAB9AACHEHSD17B1HSD17B2 | |
| SCHEMBL14417351 | 0.73 | ESR2 (0.71) | ACHEHSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |