Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 6/20 | 0.60 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NCK1 | P16333 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | CCR8 | P51685 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11344954 | 0.90 | CYP1A2 (0.62) | CYP1A2CYP2A6TDP1CA12CA9 | |
| SCHEMBL13680576 | 0.77 | ENPP3 (0.44) | PIN1 | |
| SCHEMBL308248 | 0.76 | CYP1A2 (1.00) | CYP1A2CYP2A6TDP1CA12CA9 | |
| SCHEMBL29389285 | 0.76 | CYP1A2 (1.00) | CYP1A2CYP2A6TDP1CA12CA9 | |
| SCHEMBL29399131 | 0.74 | CYP1A2 (1.00) | CYP1A2CYP2A6TDP1CA12CA9 | |
| SCHEMBL10882775 | 0.74 | CYP1A2 (0.93) | CYP1A2CYP2A6TDP1CA12CA9 | |
| Ammonia Solution, Strong SCHEMBL28805667 | 0.74 | CYP2A6 (0.93) | CYP1A2CYP2A6TDP1CA12CA9 | |
| SCHEMBL425085 | 0.74 | CYP1A2 (1.00) | CYP1A2CYP2A6TDP1CA12CA9 | |
| Methane SCHEMBL28761144 | 0.74 | CYP1A2 (0.93) | CYP1A2CYP2A6TDP1CA12CA9 | |
| Water SCHEMBL27539226 | 0.74 | CYP1A2 (0.93) | CYP1A2CYP2A6TDP1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114437072-B | Synthesis method of 6-methylisoindolo [2,1-a ] quinoxaline compound | 中国科学院大连化学物理研究所 | 2023-03-31 | — | — | CN | claimed |
| CN-114920911-B | Method for producing polyisothiaindene conductive polymer | 株式会社力森诺科 | 2024-05-03 | — | — | CN | disclosed |
| CN-114437072-B | Synthesis method of 6-methylisoindolo [2,1-a ] quinoxaline compound | 中国科学院大连化学物理研究所 | 2023-03-31 | — | — | CN | disclosed |
| EP-4129407-A1 | ARYL, HETEROARYL, AND HETEROCYCLIC COMPOUNDS FOR TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Achillion Pharmaceuticals, Inc. (US) | 2023-02-08 | — | — | EP | disclosed |
| WO-2022212296-A1 | ARYL HETEROCYCLIC COMPOUNDS AS Kv1.3 POTASSIUM SHAKER CHANNEL BLOCKERS | D.E. SHAW RESEARCH, LLC (US) | 2022-10-06 | — | — | WO | disclosed |
| CN-114920911-A | Method for producing polyisothianaphthene-based conductive polymer | 昭和电工株式会社 | 2022-08-19 | — | — | CN | disclosed |
| CN-110121516-B | Method for producing polyisothianaphthene-based conductive polymer | 昭和电工株式会社 | 2022-07-01 | — | — | CN | disclosed |
| CN-114437072-A | Synthetic method of 6-methylisoindolo [2,1-a ] quinoxaline compound | 中国科学院大连化学物理研究所 | 2022-05-06 | — | — | CN | disclosed |
| US-11178870-B2 | Pyridone compounds and agricultural and horticultural fungicides containing the same as active ingredients | MITSUI CHEMICALS AGRO, INC. (JP) | 2021-11-23 | — | — | US | disclosed |
| US-11183340-B2 | Method for manufacturing solid electrolytic capacitor | SHOWA DENKO K.K. (JP) | 2021-11-23 | — | — | US | disclosed |
| US-20160002188-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR INHIBITION OF FASN | FORMA THERAPEUTICS, INC. | 2016-01-07 | — | — | US | disclosed |
| WO-2015130838-A1 | ARYL, HETEROARYL, AND HETEROCYCLIC COMPOUNDS FOR TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ACHILLION PHARMACEUTICALS, INC. (US) | 2015-09-03 | — | — | WO | disclosed |
| US-20150239895-A1 | Aryl, Heteroaryl, and Heterocyclic Compounds for Treatment of Complement Mediated Disorders | ACHILLION PHARMACEUTICALS, INC. (US) | 2015-08-27 | — | — | US | disclosed |
| WO-2014164749-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR INHIBITION OF FASN | FORMA THERAPEUTICS, INC. (US) | 2014-10-09 | — | — | WO | disclosed |
| WO-2014164767-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR INHIBITION OF FASN | FORMA THERAPEUTICS, INC. (US) | 2014-10-09 | — | — | WO | disclosed |
| WO-2013051625-A1 | METHOD FOR PRODUCING MEGAKARYOCYTES AND/OR PLATELETS FROM PLURIPOTENT STEM CELLS | 日産化学工業株式会社 (JP) | 2013-04-11 | — | — | WO | disclosed |
| WO-2010140685-A1 | HETEROCYCLIC COMPOUND AND HEMATOPOIETIC STEM CELL AMPLIFIER | 日産化学工業株式会社 (JP) | 2010-12-09 | — | — | WO | disclosed |
| US-4954590-A | SUBJECTING ISOINDOLINE ISOINDOLE COMPOUND TO OXIDATIVE POLYMERIZATION; ELECTROCONDUCTIVE POLYMER | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1990-09-04 | — | — | US | disclosed |
| US-4833231-A | Polymer having isoindole structure | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1989-05-23 | — | — | US | disclosed |
| EP-0248915-A1 | POLYMERS HAVING ISOINDOLE STRUCTURE AND PROCESS FOR THEIR PREPARATION | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1987-12-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11178870-B2 | Pyridone compounds and agricultural and horticultural fungicides containing the same as active ingredients | PNPO, CYP4X1, PDXK | CYP1A2 6/4885CYP2A6 42/4885TDP1 945/4885 |
| US-20150239895-A1 | Aryl, Heteroaryl, and Heterocyclic Compounds for Treatment of Complement Mediated Disorders | TFPI, CFD, F3 | CYP1A2 2103/4885CYP2A6 3737/4885TDP1 3474/4885 |
| US-20160002188-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR INHIBITION OF FASN | FASN, FABP1, SCD | CYP1A2 582/4885CYP2A6 594/4885TDP1 3567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.