SCHEMBL13680582

SCHEMBL13680582

Cc1cc(C(F)(F)F)n(C)c1

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16418630 0.80 ALDH1A1 (0.32)
SCHEMBL22693491 0.71 PDK2 (0.30)
SCHEMBL7993955 0.70
SCHEMBL22251112 0.70 BRD4 (0.35) HTT
SCHEMBL27934808 0.70 CYP11B2 (0.35)
SCHEMBL20843904 0.67
SCHEMBL6234598 0.67 IDH1 (0.37)
SCHEMBL15721251 0.62 XPO1 (0.36) HTT
SCHEMBL20843915 0.62
SCHEMBL21479579 0.60 HSD11B1 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021143677-A1 FUSED RING SUBSTITUTED AROMATIC COMPOUND AND PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION, AND USE THEREOF 青岛清原化合物有限公司 2021-07-22 WO disclosed
US-7582658-B2 Bicyclic compound ASAHI KASEI PHARMA CORPORATION (JP) 2009-09-01 US disclosed
US-7582658-B2 Bicyclic compound ASAHI KASEI PHARMA CORPORATION (JP) 2009-09-01 US disclosed