Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21128719 | 0.82 | TAAR1 (0.44) | LTA4HALDH1A1TAAR1KDM4EHPGD | |
| SCHEMBL13180060 | 0.79 | TSHR (0.56) | ALDH1A1LMNAL3MBTL1MAPT | |
| SCHEMBL24349082 | 0.77 | CHRM2 (0.53) | LTA4HIDH1TAAR1 | |
| SCHEMBL27719076 | 0.77 | IDH1 (0.58) | CALM1LTA4HIDH1ALDH1A1LMNA | |
| SCHEMBL24349085 | 0.73 | IDH1 (0.47) | CALM1LTA4HIDH1ALDH1A1TAAR1 | |
| SCHEMBL1244707 | 0.72 | CALM1 (0.46) | CALM1LTA4HIDH1ALDH1A1LMNA | |
| Diphenylmethane SCHEMBL27450549 | 0.71 | CALM1 (0.86) | CALM1LTA4HIDH1ALDH1A1ATM | |
| Diphenylmethane SCHEMBL3792579 | 0.71 | CALM1 (1.00) | CALM1LTA4HIDH1ALDH1A1LMNA | |
| Diphenylmethane SCHEMBL4361124 | 0.71 | CALM1 (1.00) | CALM1LTA4HIDH1ALDH1A1LMNA | |
| Diphenylmethane SCHEMBL14763944 | 0.71 | CALM1 (1.00) | CALM1LTA4HIDH1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9580438-B2 | Bifluorodioxalane-amino-benzimidazole kinase inhibitors for the treatment of cancer, autoimmuneinflammation and CNS disorders | 4SC DISCOVERY GMBH (DE) | 2017-02-28 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |