Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 3/20 | 0.50 |
| ▸ | AHR | P35869 | 4/20 | 0.47 |
| ▸ | CMA1 | P23946 | 2/20 | 0.47 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 2/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.43 |
| ▸ | CACNG8 | Q8WXS5 | 2/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 3/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680600 | 0.88 | GRIA1 (0.57) | CRBNAHRBRD4CREBBPGRIA1 | |
| SCHEMBL16321522 | 0.79 | CRBN (0.47) | CRBNAHRCMA1EIF2AK2BRD4 | |
| SCHEMBL6745200 | 0.78 | CRBN (0.49) | CRBNAHRCMA1EIF2AK2BRD4 | |
| SCHEMBL13529011 | 0.78 | CRBN (0.61) | CRBNAHRCMA1EIF2AK2BRD4 | |
| SCHEMBL13680973 | 0.76 | CRBN (0.42) | CRBNAHRCMA1EIF2AK2BRD4 | |
| SCHEMBL5873706 | 0.75 | TDP2 (0.70) | CRBNAHRCMA1EIF2AK2BRD4 | |
| SCHEMBL8265611 | 0.73 | CRBN (0.61) | CRBNAHRCMA1EIF2AK2BRD4 | |
| SCHEMBL4408889 | 0.73 | TDP2 (0.65) | CRBNAHRCMA1EIF2AK2BRD4 | |
| SCHEMBL16322576 | 0.72 | CMA1 (0.46) | CRBNAHRCMA1EIF2AK2BRD4 | |
| SCHEMBL278958 | 0.72 | AHR (0.61) | CRBNAHRCMA1EIF2AK2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |