Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CCR1 | P32246 | 1/20 | 0.46 |
| ▸ | CCR8 | P51685 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680585 | 0.84 | KIF11 (0.56) | ALDH1A1TP53POLBCCR1CCR8 | |
| SCHEMBL12270039 | 0.79 | KMT2A (0.61) | CYP1A2ALDH1A1TP53HSD17B10POLB | |
| SCHEMBL13680665 | 0.79 | CCR1 (0.50) | ALDH1A1HSD17B10POLBCCR1CCR8 | |
| SCHEMBL3422361 | 0.77 | CCR1 (0.75) | ALDH1A1HSD17B10POLBCCR1CCR8 | |
| SCHEMBL13537053 | 0.77 | SMN1; SMN2 (0.49) | TP53TSHRPOLBCCR1CCR8 | |
| SCHEMBL13680553 | 0.77 | GBA1 (0.52) | ALDH1A1TP53TSHRPOLBKMT2A | |
| SCHEMBL13680483 | 0.76 | TSHR (0.49) | TP53TSHRKMT2AMEN1MAPT | |
| SCHEMBL13680667 | 0.73 | CCR1 (0.52) | ALDH1A1HSD17B10POLBCCR1CCR8 | |
| SCHEMBL2483166 | 0.73 | KMT2A (0.72) | CYP1A2ALDH1A1TP53KMT2AMEN1 | |
| SCHEMBL30070833 | 0.73 | KMT2A (0.72) | CYP1A2ALDH1A1TP53KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |