Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.46 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | HNF4A | P41235 | 1/20 | 0.40 |
| ▸ | ADH1B | P00325 | 1/20 | 0.39 |
| ▸ | ADH1C | P00326 | 1/20 | 0.39 |
| ▸ | ADH1A | P07327 | 1/20 | 0.39 |
| ▸ | ADH7 | P40394 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.38 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19258592 | 0.88 | MEN1 (0.43) | ADH1BADH1CADH1AADH7MAOA | |
| SCHEMBL26988123 | 0.86 | MAOB (0.41) | MTNR1AMTNR1BFDFT1IDH1MAOA | |
| SCHEMBL7083313 | 0.82 | CALM1 (0.52) | MTNR1AMTNR1BCALM1FDFT1IDH1 | |
| Dihydrocinnamaldehyde SCHEMBL1335 | 0.81 | ADH1B (0.50) | ADH1BADH1CADH1AADH7GPR52 | |
| SCHEMBL418611 | 0.81 | GPR52 (0.50) | ADH1BADH1CADH1AADH7ACMSD | |
| SCHEMBL13313975 | 0.80 | MEN1 (0.38) | ADH1BADH1CADH1AADH7MAOA | |
| Dihydrocinnamaldehyde SCHEMBL19810527 | 0.79 | ADH1B (0.48) | ADH1BADH1CADH1AADH7GPR52 | |
| Dihydrocinnamaldehyde SCHEMBL5791873 | 0.79 | ADH1B (0.48) | ADH1BADH1CADH1AADH7GPR52 | |
| Dihydrocinnamaldehyde SCHEMBL11053918 | 0.79 | ADH1B (0.48) | ADH1BADH1CADH1AADH7GPR52 | |
| SCHEMBL19313659 | 0.79 | CALM1 (0.60) | MTNR1AMTNR1BCALM1FDFT1IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |