Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.42 |
| ▸ | DEGS1 | O15121 | 4/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.31 |
| ▸ | ABAT | P80404 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19555364 | 0.80 | ESR1 (0.44) | ESR1ESR2DEGS1ALDH5A1ABAT | |
| SCHEMBL31212506 | 0.77 | CA12 (0.37) | — | |
| SCHEMBL13680816 | 0.77 | DAO (0.35) | — | |
| SCHEMBL13680819 | 0.77 | DAO (0.46) | — | |
| SCHEMBL22151010 | 0.77 | CA12 (0.37) | — | |
| SCHEMBL6197859 | 0.77 | CCR1 (0.40) | — | |
| SCHEMBL1639271 | 0.77 | GBA1 (0.39) | — | |
| SCHEMBL28018963 | 0.77 | ESR1 (0.39) | ESR1ESR2DEGS1 | |
| SCHEMBL19090102 | 0.77 | ESR1 (0.39) | ESR1ESR2DEGS1FFAR1 | |
| SCHEMBL2429377 | 0.75 | ESR1 (0.47) | ESR1ESR2DEGS1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |