Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31591297 | 0.80 | L3MBTL1 (0.37) | DAOL3MBTL1NFE2L2MAOBPTK2 | |
| SCHEMBL3882488 | 0.80 | L3MBTL1 (0.37) | DAOL3MBTL1NFE2L2MAOBPTK2 | |
| SCHEMBL13680812 | 0.77 | ESR1 (0.42) | — | |
| SCHEMBL31212506 | 0.77 | CA12 (0.37) | ADRA2AADRA2BADRA2C | |
| SCHEMBL22151010 | 0.77 | CA12 (0.37) | ADRA2AADRA2BADRA2C | |
| SCHEMBL13680819 | 0.77 | DAO (0.46) | DAOL3MBTL1ALDH1A1 | |
| SCHEMBL6197859 | 0.77 | CCR1 (0.40) | DAOKDM4EALDH1A1PLAUADRA2A | |
| SCHEMBL1639271 | 0.77 | GBA1 (0.39) | KDM4ETSHRALDH1A1PLAUADRA2A | |
| SCHEMBL27667500 | 0.77 | DAO (0.33) | DAOL3MBTL1NFE2L2MAOBKDM4E | |
| SCHEMBL14737586 | 0.76 | HTR1A (0.39) | DAOL3MBTL1MAOBPTK2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |