Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.31 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29566630 | 0.80 | DAO (0.41) | DAOHTR2AHTR2CKCNH2ALDH1A1 | |
| SCHEMBL1288362 | 0.80 | DAO (0.41) | DAOHTR2AHTR2CKCNH2ALDH1A1 | |
| SCHEMBL6197859 | 0.77 | CCR1 (0.40) | DAOALDH1A1 | |
| SCHEMBL13680816 | 0.77 | DAO (0.35) | DAOALDH1A1L3MBTL1 | |
| SCHEMBL22151010 | 0.77 | CA12 (0.37) | — | |
| SCHEMBL1639271 | 0.77 | GBA1 (0.39) | ALDH1A1MBOAT4 | |
| SCHEMBL31212506 | 0.77 | CA12 (0.37) | — | |
| SCHEMBL13680812 | 0.77 | ESR1 (0.42) | — | |
| SCHEMBL8647725 | 0.77 | DAO (0.50) | DAOALDH1A1L3MBTL1MBOAT4 | |
| SCHEMBL14737894 | 0.76 | DAO (0.39) | DAOHTR2AHTR2CKCNH2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |